Sadelain, Michele: search on Z-Library

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1

Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Eyquem, Justin, Mansilla-Soto, Jorge, Giavridis, Theodoros, van der Stegen, Sjoukje J. C., Hamieh, Mohamad, Cunanan, Kristen M., Odak, Ashlesha, Gönen, Mithat, Sadelain, Michel

Journal:

Year:

2017

Language:

english

File:

PDF, 4.98 MB

english, 2017

2

Chimeric Antigen Receptor Therapy

Longo, Dan L., June, Carl H., Sadelain, Michel

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 1010 KB

english, 2018

3

The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells

Mestermann, Katrin, Giavridis, Theodoros, Weber, Justus, Rydzek, Julian, Frenz, Silke, Nerreter, Thomas, Mades, Andreas, Sadelain, Michel, Einsele, Hermann, Hudecek, Michael

Journal:

Science Translational Medicine

Year:

2019

Language:

english

File:

PDF, 2.77 MB

english, 2019

4

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

Themeli, Maria, Kloss, Christopher C, Ciriello, Giovanni, Fedorov, Victor D, Perna, Fabiana, Gonen, Mithat, Sadelain, Michel

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 2.68 MB

english, 2013

5

Reprint of: Building a Safer and Faster CAR: Seatbelts, Airbags, and CRISPR

Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel

Journal:

Biology of Blood and Marrow Transplantation

Year:

2018

Language:

english

File:

PDF, 258 KB

english, 2018

6

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

Maher, John, Brentjens, Renier J., Gunset, Gertrude, Rivière, Isabelle, Sadelain, Michel

Journal:

Nature Biotechnology

Year:

2002

Language:

english

File:

PDF, 1.76 MB

english, 2002

7

A Promising Genetic Approach to the Treatment of b-Thalassemia

Chad May, Michel Sadelain

Journal:

Trends in Cardiovascular Medicine

Year:

2001

Language:

english

File:

PDF, 337 KB

english, 2001

8

How do CARs work?

Davila, Marco L., Brentjens, Renier, Wang, Xiuyan, Rivière, Isabelle, Sadelain, Michel

Journal:

Year:

2012

Language:

english

File:

PDF, 783 KB

english, 2012

9

Chimeric Antigen Receptors: A Paradigm Shift in Immunotherapy

Sadelain, Michel

Journal:

Annual Review of Cancer Biology

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

10

CD19 CAR T Cells

Sadelain, Michel

Journal:

Year:

2017

Language:

english

File:

PDF, 428 KB

english, 2017

11

Gene Therapy and Genome Editing

Boulad, Farid, Mansilla-Soto, Jorge, Cabriolu, Annalisa, Rivière, Isabelle, Sadelain, Michel

Journal:

Hematology/Oncology Clinics of North America

Year:

2018

Language:

english

File:

PDF, 548 KB

english, 2018

12

Early experience using salvage radiotherapy for relapsed/refractory nonâHodgkin lymphomas after CD19 chimericÂ antigen receptor (CAR)Â T cell therapy

Imber, Brandon S., Sadelain, Michel, DeSelm, Carl, Batlevi, Connie, Brentjens, Renier J., Dahi, Parastoo B., Giralt, Sergio, Park, Jae H., Sauter, Craig, Scordo, Michael, Shah, Gunjan, Perales, Miguel

Journal:

British Journal of Haematology

Year:

2020

File:

PDF, 650 KB

2020

13

Globin gene transfer for the treatment of severe hemoglobinopathies: a paradigm for stem cell-based gene therapy

Michel Sadelain

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

14

The promise and potential pitfalls of chimeric antigen receptors

Michel Sadelain, Renier Brentjens, Isabelle Rivière

Journal:

Current Opinion in Immunology

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

15

10.1038/2569

Sadelain, Michel, Kieff, Elliott

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 56 KB

english, 1998

16

10.1038/35017565

Sadelain, Michel, May, Chad, Rivella, Stefano, Callegari, John, Heller, Glenn, Gaensler, Karen M. L., Luzzatto, Lucio

Journal:

Year:

2000

Language:

english

File:

PDF, 291 KB

english, 2000

17

Safe harbours for the integration of new DNA in the human genome

Sadelain, Michel, Papapetrou, Eirini P., Bushman, Frederic D.

Journal:

Nature Reviews Cancer

Year:

2011

Language:

english

File:

PDF, 321 KB

english, 2011

18

T cell activation upon exposure to patient-derived tumor tissue: A functional assay to select patients for adoptive T cell therapy

Caroline Schroten, Robert Kraaij, Joke L.M. Veldhoven, Cor A. Berrevoets, Michael A. den Bakker, Qiangzhong Ma, Michel Sadelain, Chris H. Bangma, Ralph A. Willemsen, Reno Debets

Journal:

Journal of Immunological Methods

Year:

2010

Language:

english

File:

PDF, 629 KB

english, 2010

19

Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies

Mark Przybylowski, Shirley Bartido, Oriana Borquez-Ojeda, Michel Sadelain, Isabelle Rivière

Journal:

Year:

2007

Language:

english

File:

PDF, 894 KB

english, 2007

20

Toward gene therapy for disorders of globin synthesis

John Tisdale, Michel Sadelain

Journal:

Seminars in Hematology

Year:

2001

Language:

english

File:

PDF, 1.38 MB

english, 2001

21

Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells

Kloss, Christopher C, Condomines, Maud, Cartellieri, Marc, Bachmann, Michael, Sadelain, Michel

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 555 KB

english, 2012

22

The Genetic Engineering of Hematopoietic Stem Cells: the Rise of Lentiviral Vectors, the Conundrum of the LTR, and the Promise of Lineage-restricted Vectors

Chang, Alex H, Sadelain, Michel

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 214 KB

english, 2007

23

Globin gene transfer for treatment of the β-thalassemias and sickle cell disease

Michel Sadelain, Stefano Rivella, Leszek Lisowski, Selda Samakoglu, Isabelle Rivière

Journal:

Best Practice & Research Clinical Haematology

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

24

Eliminating Cells Gone Astray

Sadelain, Michel

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 372 KB

english, 2011

25

CAR T cell therapy and the promise of T cell engineering

Sadelain, Michel

Journal:

Experimental Hematology

Year:

2014

Language:

english

File:

PDF, 34 KB

english, 2014

26

Functional Assessment of the Engraftment Potential of Gammaretrovirus-Modified CD34 + Cells, Using a Short Serum-Free Transduction Protocol

Budak-Alpdogan, Tulin, Przybylowski, Mark, Gonen, Mithat, Sadelain, Michel, Bertino, Joseph, Rivière, Isabelle

Journal:

Human Gene Therapy

Year:

2006

Language:

english

File:

PDF, 14.02 MB

english, 2006

27

Gene Therapy for Homozygous β -thalassemia. Is it a Reality?

Boulad, Farid, Rivière, Isabelle, Sadelain, Michel

Journal:

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

28

Therapeutic Options for Patients with Severe β-Thalassemia: The Need for Globin Gene Therapy

Sadelain, Michel, Boulad, Farid, Galanello, Renzo, Giardina, Patricia, Locatelli, Franco, Maggio, Aurelio, Rivella, Stefano, Riviere, Isabelle, Tisdale, John

Journal:

Human Gene Therapy

Year:

2007

Language:

english

File:

PDF, 7.22 MB

english, 2007

29

The pharmacology of second-generation chimeric antigen receptors

van der Stegen, Sjoukje J. C., Hamieh, Mohamad, Sadelain, Michel

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 462 KB

english, 2015

30

The quest for spatio-temporal control of CAR T cells

Sun, Jie, Sadelain, Michel

Journal:

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

31

Generation of a High-Titer Retroviral Vector Capable of Expressing High Levels of the Human β-Globin Gene

Michel Sadelain, C. H. Jason Wang, Michael Antoniou, Frank Grosveld and Richard C. Mulligan

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

32

Issues in the manufacture and transplantation of genetically modified hematopoietic stem cells

Sadelain, Michel, Frassoni, Francesco, Rivi??re, Isabelle

Journal:

Current Opinion in Hematology

Year:

2000

Language:

english

File:

PDF, 193 KB

english, 2000

33

Biology and clinical application of CAR T cells for B cell malignancies

Davila, Marco L., Sadelain, Michel

Journal:

International Journal of Hematology

Year:

2016

Language:

english

File:

PDF, 802 KB

english, 2016

34

Recent advances in globin gene transfer for the treatment of beta-thalassemia and sickle cell anemia

Sadelain, Michel

Journal:

Current Opinion in Hematology

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

35

Therapeutic T cell engineering

Sadelain, Michel, Rivière, Isabelle, Riddell, Stanley

Journal:

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

36

Cytokine Release Syndrome Grade is a Predictive Marker for Infections in Relapsed or Refractory B-cell All Patients Treated with CAR T Cells

Park, Jae H, Romero, F Andres, Taur, Ying, Sadelain, Michel, Brentjens, Renier J, Hohl, Tobias M, Seo, Susan K

Journal:

Clinical Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 634 KB

english, 2018

37

Engineering Converted Autologous Hematopoietic Stem Cells From Vascular Endothelial for Treatment of Hemoglobinopathies

Lis, Raphael, Mansilla-Soto, Jorge, Duran, Jose Gabriel Barcia, Lu, Tyler, Sadelain, Michel, Rafii, Shahin

Journal:

Experimental Hematology

Year:

2018

Language:

english

File:

PDF, 59 KB

english, 2018

38

Activation conditions determine susceptibility of murine primary T-lymphocytes to retroviral infection

Andrea B. Hagani, Isabelle Rivière, Cuiwen Tan, Anja Krause, Michel Sadelain

Journal:

The Journal of Gene Medicine

Year:

1999

Language:

english

File:

PDF, 179 KB

english, 1999

39

Fulminant experimental autoimmune encephalo-myelitis induced by retrovirally mediated TCR gene transfer

Amy L. Stolzer, Michel Sadelain, Derek B. Sant'Angelo

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 364 KB

english, 2005

40

Induction of autoantibodies to syngeneic prostate-specific membrane antigen by xenogeneic vaccination

Polly D. Gregor, Jedd D. Wolchok, Vandana Turaga, Jean-Baptiste Latouche, Michel Sadelain, Dean Bacich, Warren D.W. Heston, Alan N. Houghton, Howard I. Scher

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

41

Estimation of empirical null using a mixture of normals and its use in local false discovery rate

DoHwan Park, Junyong Park, Xiaosong Zhong, Michel Sadelain

Journal:

Computational Statistics & Data Analysis

Year:

2011

Language:

english

File:

PDF, 396 KB

english, 2011

42

GENETIC TREATMENT OF THE HAEMOGLOINOPATHIES: RECOMBINATIONS AND NEW COMBINATIONS

Michel Sadelain

Journal:

British Journal of Haematology

Year:

1997

Language:

english

File:

PDF, 383 KB

english, 1997

43

Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer

Chunsheng Liu, Kosei Hasegawa, Stephen J. Russell, Michel Sadelain, Kah-Whye Peng

Journal:

Year:

2009

Language:

english

File:

PDF, 719 KB

english, 2009

44

A Genetic Strategy for Single and Combinatorial Analysis of miRNA Function in Mammalian Hematopoietic Stem Cells

Eirini P. Papapetrou, James E. Korkola, Michel Sadelain

Journal:

Year:

2010

Language:

english

File:

PDF, 790 KB

english, 2010

45

Animal models and molecular imaging tools to investigate lymph node metastases

Elliot L. Servais, Christos Colovos, Adam J. Bograd, Julie White, Michel Sadelain, Prasad S. Adusumilli

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 765 KB

english, 2011

46

[131I]FIAU labeling of genetically transduced, tumor-reactive lymphocytes: cell-level dosimetry and dose-dependent toxicity

Pat Zanzonico, Guenther Koehne, Humilidad F. Gallardo, Mikhail Doubrovin, Ekaterina Doubrovina, Ronald Finn, Ronald G. Blasberg, Isabelle Riviere, Richard J. O’Reilly, Michel Sadelain, Steven M. Larso

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

47

Chronic inflammation in tumor stroma is an independent predictor of prolonged survival in epithelioid malignant pleural mesothelioma patients

Kei Suzuki, Kyuichi Kadota, Camelia S. Sima, Michel Sadelain, Valerie W. Rusch, William D. Travis, Prasad S. Adusumilli

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

48

Immune responses and immunotherapeutic interventions in malignant pleural mesothelioma

Adam J. Bograd, Kei Suzuki, Eva Vertes, Christos Colovos, Eduardo A. Morales, Michel Sadelain, Prasad S. Adusumilli

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 1.84 MB

english, 2011

49

Adoptive-transfer therapy of tumors with the tumor-specific primary cytotoxic T cells induced in vitro with the B7.1-transduced MCA205 cell line

Sun Jung Kim, Michel Sadelain, Jeong-Soon Lee, Roh Hyun Seong, Yeon-Sook Yun, Young Ju Jang, Hee Young Chung

Journal:

Cancer Immunology, Immunotherapy

Year:

1999

Language:

english

File:

PDF, 147 KB

english, 1999

50

Current status of globin gene therapy for the treatment of β-thalassaemia

Leszek Lisowski, Michel Sadelain

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 158 KB

english, 2008

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